Browsing by Author "Cruz-Reyes, Jorge"
Now showing items 1-11 of 11
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Kostomiris, Demetrios Harry (2021-07-23)The single-celled pathogens Mycobacterium tuberculosis and Trypanosoma cruzi are the causative agents of the human diseases tuberculosis and Chagas disease, respectively. In an effort to develop potentially new treatments ...
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Shubina-McGresham, Maria (2012-10-19)Characterization of allosteric properties of phosphofructokinase from the extreme thermophile Thermus thermophilus (TtPFK) using thermodynamic linkage analysis revealed several peculiarities. Inhibition and activation of ...
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Kumar, Vikas (2016-04-25)Trypanosoma brucei requires extensive remodeling of its mitochondrial gene expression during different stages of its life cycle. RNA editing is one of the vital processes for these mitochondrial changes. This process ...
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Benavides, Lucille H (Texas A&M University, 2006-04-12)The eastern subterranean termite, Reticulitermes flavipes, is the most widely dispersed termite in North America. The genus Reticulitermes spp. is responsible for 80% of total termite damage caused to urban structures each ...
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Song, Jiarui (2021-03-25)Telomerase is a specialized ribonucleoprotein (RNP) complex responsible for telomere maintenance. Telomerase consists of three essential components: the catalytic subunit telomerase reverse transcriptase TERT, the telomerase ...
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Reifur, Larissa; Yu, Laura E.; Cruz-Reyes, Jorge; vanHartesvelt, Michelle; Koslowsky, Donna J.; Maas, Stefan (PloS One, 2010)
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Osborne, Edith Marie (Texas A&M University, 2007-04-25)The hammerhead ribozyme (HHRz) catalyzes a site-specific phosphodiester bond cleavage reaction that is enhanced by the presence of metal cations. Metal cations are thought to aid in the folding and possibly the catalytic ...
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Madina, Bhaskara R.; Kumar, Vikas; Mooers, Blaine H. M.; Cruz-Reyes, Jorge (PLOS, 2015-04-30)Adaptation and survival of Trypanosoma brucei requires editing of mitochondrial mRNA by uridylate (U) insertion and deletion. Hundreds of small guide RNAs (gRNAs) direct the mRNA editing at over 3,000 sites. RNA editing ...
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Hernandez, Alfredo J. (2012-02-14)RNA editing in trypanosomes is the post-transcriptional insertion or deletion of uridylates at specific sites in mitochondrial mRNAs. This process is catalyzed by a multienzyme, multisubunit complex through a series of ...
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Cornish, Peter Verle (Texas A&M University, 2006-04-12)Plant luteoviral RNA viruses employ -1 frameshifting for the production of P1 and P1-P2 fusion proteins important for viral replication. Luteoviral pseudoknots are characterized by three adenosines in the 3' side of loop ...
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Meehan, Joshua Everett (2023-05-11)T. brucei is a protozoan parasite which is the causative agent of African Sleeping Sickness. It undergoes a complex lifecycle as it switches between its insect vector and mammalian hosts. Mitochondrial mRNAs are genomically ...